Dynamic Characteristics Analysis and Mooring System Optimization of Wreck Salvage in Off-Bottom Stage Based on Seabed Resistance Force Time History

In this paper, a method for analyzing the dynamic characteristics opi meet my decorator of the sunken ship salvage system based on the accurate time history of the seabed resistance force is proposed.The simulation of a typical case preliminarily clarifies the complex interaction mode between the mother ship (a barge), the mooring line, and the lif

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Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

Sickle cell disease (SCD) is caused by a single-point mutation, and the ensuing deoxygenation-induced polymerization of sickle hemoglobin (HbS), and reduction in bioavailability of vascular nitric oxide (NO), contribute to the pathogenesis of the disease.In a proof-of-concept study, we successfully incorporated nitrate ester groups onto two previou

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Caenorhabditis elegans histone methyltransferase MET-2 shields the male X chromosome from checkpoint machinery and mediates meiotic sex chromosome inactivation.

Meiosis is a specialized form of cellular division that results finish line thia cal in the precise halving of the genome to produce gametes for sexual reproduction.Checkpoints function during meiosis to detect errors and subsequently to activate a signaling cascade that prevents the formation of aneuploid gametes.Indeed, asynapsis of a homologous

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